Adeno-associated virus: a Trojan Horse for Transgene Delivery
AAV is a tool for packaging and delivering a transgene to a cell’s nucleus and has become a go-to method for researchers studying the central nervous system. By delivering a transgene via AAV, researchers can manipulate neuronal function to better understand how neurons and their circuits work
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Cre-lox Recombination: A Tool for Cell-Specific DNA Manipulation
Cre recombinase is an enzyme derived from the P1 bacteriophage that recognizes a specific type of DNA segment called a LoxP site. Cre recombinase will manipulate DNA that is located between two LoxP sites depending on the LoxP orientation.
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